21c Museum Hotel,Louisville Kentucky

If a vacation for you is all about visiting museums, and you're partial to modern art, you absolutely must make your next destination Louisville, Kentucky.  Yes, we said Louisville.  No, we're not kidding.  This sleepy, southern city is now the home of the 21c Museum Hotel, the first-ever hotel that – as its name suggests -- doubles as a museum.  So visitors can soak up all the culture they want without even leaving the premises!

The name 21c refers to the 21^st century, as all work displayed in the property's public spaces and galleries has been and will be created by artists who are living and working right now.  In addition to modern art, the 91-room hotel boasts all the modern amenities, including pre-loaded iPods for guests, HDTV flat screen TV's, Wi-Fi, modern bedrooms, luxury linens and bath amenities and the usual trappings of an upscale hotel.  For some reason, they're also partial to penguins, which are something of a recurring theme at the property.  If you're an art lover, this may be the ideal vacation spot for you.  But if Louisville's charms don't exactly beckon, hang tight.  21c is set to open a second hotel in Austin, Texas – with the addition of a residential wing.  So if vacationing in a museum just isn't enough, you can actually live in one.